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Condition:

Byetta^®
(exenatide) injection Capastat^® Sulfate
(capreomycin for injection, USP) Cialis^®
(tadalafil) Cymbalta^®
(duloxetine hydrochloride) Evista^®
(raloxifene HCl) Forteo^®
(teriparatide [rDNA origin] injection) Lilly Glucagon
(glucagon by injection [rDNA origin]) Humalog^®
(insulin lispro injection [rDNA origin]) Humalog^® Mix50/50™
(50% insulin lispro protamine suspension, 50% insulin lispro injection [rDNA origin]) Humalog^® Mix75/25™
(75% insulin lispro protamine suspension, 25% insulin lispro injection [rDNA origin]) Humulin^®
(human insulin [rDNA origin]) Humatrope^®
(somatropin [rDNA origin] for injection) Prozac^®
(fluoxetine hydrochloride) Quinidine Gluconate Injection, USP
ReoPro^®
(abciximab) Seromycin^®
(cycloserine capsules, USP) Symbyax^®
(olanzapine and fluoxetine hydrochloride) Xigris^®
(drotrecogin alfa [activated]) Zyprexa^®
(olanzapine)

Acute Bipolar Mania Adult Growth Hormone Deficiency Bipolar Depression Diabetes Diabetic Peripheral Neuropathic Pain (DPNP) Erectile Dysfunction Idiopathic Short Stature (ISS) Major Depressive Disorder (MDD) Osteoporosis Pediatric Growth Hormone Deficiency Schizophrenia Severe Sepsis Turner Syndrome

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Cymbalta® (duloxetine HCl) is approved for the treatment of depression and generalized anxiety disorder, and for the management of diabetic peripheral neuropathic pain and fibromyalgia.

Product Information

Binding Affinities

The in vitro binding affinities of Cymbalta for the neurotransmitter reuptake transporters and receptors in the CNS are listed below.¹

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Preclinical, or in vitro, data are not necessarily indicative of clinical safety or efficacy in humans.

Although the exact mechanisms of the antidepressant, central pain inhibitory, and anxiolytic actions of duloxetine in humans are unknown, these actions are believed to be related to its potentiation of serotonergic and noradrenergic activity in the central nervous system (CNS)²

Reference:

Bymaster FP, et al. Neuropsychopharmacology. 2001;25(6):871-880.
Cymbalta full Prescribing Information, 2009.

Formulary Access Finder

Cymbalta has been added to the Anthem Blue Cross Blue Shield National Preferred Formulary.

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