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Scientific Literature

Below are published studies on clinical trials of Cymbalta.

Duloxetine, 60 mg Once Daily, for Major Depressive Disorder: A Randomized Double-Blind Placebo-Controlled Trial
This multicenter, double-blind, parallel-group study of duloxetine 60 mg/day for 9 weeks found that duloxetine is significantly superior to placebo, reducing HAM-D17 total scores and painful physical symptoms associated with MDD.

Duloxetine Treatment for Role Functioning Improvement in Generalized Anxiety Disorder: Three Independent Studies
One 9-week and two 10-week studies of Cymbalta 60 and 120 mg/day found that patients treated with duloxetine improved significantly more than those treated with placebo, as measured by the Sheehan Disability Scale work, social life, and family/home responsibility scores. Each of these studies were randomized, double-blind, placebo-controlled multicenter trials.

Cymbalta for Fibromyalgia

Cymbalta is indicated for the management of fibromyalgia.

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